A Powerful Supplement With Many Benefits

Our Recommendation €25.95 : Swanson Berberine 60 Cap (Two Month Supply)


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Berberine, a natural compound found in various plants like barberry, goldenseal, and Oregon grape, has gained recognition for its potential health benefits when used as a supplement. Numerous studies have highlighted the following advantages of berberine:

1. Weight Management: Berberine has been linked to potential benefits in weight management. It may help regulate appetite, enhance fat metabolism, and inhibit the formation of new fat cells. These mechanisms make berberine an attractive supplement for individuals seeking support in achieving healthy weight loss goals.

2. Blood Sugar Regulation: Berberine has been extensively studied for its ability to support healthy blood sugar levels. Research suggests that it can improve insulin sensitivity, enhance glucose metabolism, and reduce the production of glucose in the liver. These effects make berberine a promising supplement for individuals with diabetes or those aiming to manage their blood sugar levels.

3. Cholesterol Management: Berberine has shown promise in promoting healthy cholesterol levels. Studies indicate that it can help reduce total cholesterol, LDL (bad) cholesterol, and triglyceride levels while increasing HDL (good) cholesterol. By modulating lipid metabolism, berberine may contribute to maintaining cardiovascular health.

4. Gut Health Promotion: The antimicrobial and anti-inflammatory properties of berberine make it beneficial for promoting a healthy gut. It may help combat harmful bacteria, reduce inflammation, and support the balance of gut microbiota. These effects can contribute to improved digestion, reduced gastrointestinal discomfort, and enhanced overall gut health.

5. Anti-inflammatory Effects: Berberine exhibits potent anti-inflammatory properties, which have been studied for their potential in various health conditions. It may help alleviate chronic inflammation, which is associated with several diseases, including cardiovascular issues, metabolic disorders, and certain types of cancer.

6. Antioxidant Activity: Berberine acts as an antioxidant, helping to neutralise harmful free radicals in the body. By reducing oxidative stress, it may protect cells from damage, support healthy aging, and contribute to overall well-being.

7.  Fatty Liver Management: Chronic inflammation plays a significant role in the progression of fatty liver disease. Berberine has demonstrated anti-inflammatory properties, potentially helping to reduce inflammation in the liver. By modulating inflammatory pathways, berberine may alleviate liver inflammation and promote a healthier liver environment.

8. Mood regulation: Neurotransmitter Modulation. Berberine has been shown to modulate various neurotransmitters in preclinical studies, including serotonin, dopamine, and norepinephrine. These neurotransmitters play a crucial role in mood regulation, and imbalances in their levels have been associated with depression. While these findings are promising, further clinical research is needed to determine the direct impact of berberine on depression symptoms.

Is there any scientific evidence of Berberine for Weight Loss?

Yes, there are several scientific studies that suggest berberine can support weight loss. For example, a study published in the Journal of Translational Medicine found that berberine supplementation led to significant reductions in body weight, body mass index (BMI), and waist circumference in obese individuals. Another study published in the International Journal of Clinical and Experimental Medicine found that berberine supplementation improved insulin sensitivity and reduced body weight in patients with type 2 diabetes. These studies suggest that berberine may be effective in helping with weight loss.
  • In one older 12-week study in people with obesity, taking 500 milligrams (mg) of berberine three times per day caused about 5 pounds of weight loss, on average. The participants also lost 3.6% of their body fat. Link to Study
  • Another review of 12 studies found that supplementing with berberine led to significant reductions in body weight, body mass index, and belly fat. It also decreased levels of C-reactive protein, which is a marker of inflammation. Link to Study
  • Berberine also appears to inhibit the growth of fat cells at the molecular level, which could help promote weight loss. Link to Study

What is the recommended dosage of Berberine?

The recommended dosage of berberine for weight loss is typically between 500-1500 mg per day, taken in divided doses with meals. However, it's important to consult with a healthcare professional before starting any new supplement regimen, especially if you have any pre-existing medical conditions or are taking any medications.

Is Berberine Safe to take?

Berberine is generally considered safe when taken in recommended doses. However, it can interact with certain medications, such as antibiotics and blood thinners, so it is important to consult with a healthcare provider before taking berberine if you are on any medications. 

Further Reading....

It reduces blood sugar levels

Many studies show that berberine can significantly reduce blood sugar levels in individuals with type 2 diabetes.

It seems to work via multiple different mechanisms and may help

  • decrease insulin resistance, making the blood sugar lowering hormone insulin more effective.
  • increase glycolysis, helping the body break down sugars inside cells
  • decrease sugar production in the liver
  • slow the breakdown of carbohydrates in the gut
  • increase the number of beneficial bacteria in the gut

In a 2008 study of 116 people with diabetes, taking 1 gram of berberine per day lowered fasting blood sugar by 20%.

It also lowered hemoglobin A1c (HbA1c), a marker of long-term blood sugar control, by 12% and improved blood lipids like cholesterol and triglycerides 

According to an older review of 14 studies, berberine may be as effective as certain oral diabetes drugs, including metformin, glipizide, and rosiglitazone.

It lowers cholesterol and may reduce your risk of heart disease

Heart disease is currently the leading cause of death around the globe 

Many factors that can be measured in the blood are associated with an increased risk of heart disease.

As it turns out, berberine has been shown to improve many of these factors.

According to a review of 16 studies, it could help:

  • lower total cholesterol
  • lower LDL (bad) cholesterol
  • lower blood triglycerides
  • increase HDL (good) cholesterol
  • It has also been shown to lower apolipoprotein B by 13-15% in some older studies, which is an important risk factor for heart disease 

According to some research, berberine works by inhibiting an enzyme called PCSK9. This leads to more LDL cholesterol being removed from the bloodstream 

Keep in mind that diabetes, high blood sugar levels, and obesity are also major risk factors for heart disease, all of which seem to be improved with this supplement 

Given the beneficial effects on all these risk factors, it seems likely that berberine could reduce the risk of heart disease, though more research is needed.

Berberine may also have numerous other health benefits:

  • Cancer: Test-tube and animal studies have shown that it can reduce the growth and spread of various types of cancer
  • Antioxidant and anti-inflammatory: It has been shown to have potent antioxidant and anti-inflammatory effects in some test-tube and animal studies
  • Infections: Test-tube studies show that it can reduce the growth of harmful microorganisms, including certain types of bacteria, viruses, and fungi.
  • Fatty liver: It may reduce fat build-up in the liver, which could theoretically help protect against NAFLD.
  • Heart failure: One older study showed that it improved symptoms and reduced risk of death in people with heart failure.


For further reading, detailed scientific evidence & references can be found on the excellent ressource of Healthline .com

Note: This does not constitute medical advice, always consult your GP if you are concerned about your health.

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