Official De Simone Formulation Distributor – Republic of Ireland
Probiotic.ie: Sole Official De Simone Distributor – Republic of Ireland
✅ Original De Simone formulation (includes CDS22-formula)
✅ Clinically studied 8-strain probiotic formulation
✅ Sole official distributor for the Republic of Ireland
Probiotic.ie is the sole official distributor of De Simone formulation probiotic products, including CDS22-formula, in the Republic of Ireland. All retail, wholesale, and clinical supply for Ireland is fulfilled through our Irish operation, with local fulfilment, customer support, and nationwide supply.
Previously marketed under names such as Vivomixx and VSL#3, CDS22-formula continues the original De Simone formulation developed by Professor Claudio De Simone. It is supplied in Ireland exclusively through authorised distribution, preserving the documented formulation lineage.
Probiotic.ie: Sole Official Supplier of the De Simone CDS22-formula Range in Ireland
The complete CDS22-formula range, based on the original De Simone formulation developed by Professor Claudio De Simone, supplied exclusively by Probiotic.ie as the sole official distributor for the Republic of Ireland
CDS22-Formula | Original De Simone Formulation Probiotic | 450 Billion CFU | 36 Sachets | One Month+ Pack |
€ 73.50 EUR
CDS22-formula Probiotic 450B CFU | Original De Simone Formulation | 12 Sachets
€ 25.95 EUR
CDS22-formula Probiotic 112B CFU | Original De Simone Formulation | 20 Capsules
€ 23.95 EUR
Regular price
€ 24.95 EUR
CDS22-formula Infant Drops – Original De Simone Formulation (2×5 ml Bottles)
€ 17.95 EUR
Expert Selected. Evidence Led.
Expert-Selected Supplements Trusted by Irish Customers
Beyond CDS22-formula, the same Irish team behind Ireland’s sole official De Simone distributor carefully selects a focused range of supplements for quality, formulation standards, and real-world use in Ireland. From well-researched ingredients like Berberine HCl and Lion’s Mane Mushroom to essential vitamins and minerals, every product is Probiotic.ie-curated, standards-compliant, and chosen based on evidence and Irish customer demand.
Shop Probiotics & Evidence-Led Supplements in Ireland by Category
Browse Ireland’s most searched supplement categories, including high-strength probiotics, berberine, vitamin D3, magnesium and omega-3.
Each collection is curated using real purchase data, formulation standards and ingredient transparency.
Probiotic.ie is Ireland’s official De Simone formulation distributor and a trusted source for compliant, quality-controlled food supplements with fast nationwide delivery.
Probiotic.ie’s Most Chosen Supplements in Ireland
Selected by Probiotic.ie based on repeat purchase, long-term use, and Irish customer demand.
Swanson Berberine HCl 400 mg – Premium Herbal Supplement - 60 Caps
€ 22.95 EUR
Swanson Lion’s Mane Mushroom 500mg – 60 Capsules
€ 15.95 EUR
Regular price
€ 17.95 EUR
Swanson Ashwagandha 450mg - 100 Caps
€ 15.95 EUR
Regular price
€ 17.95 EUR
Swanson Full Spectrum Milk Thistle 500mg – 100 Capsules
€ 14.95 EUR
Regular price
€ 17.95 EUR
CDS22-Formula | Original De Simone Formulation Probiotic | 450 Billion CFU | 36 Sachets | One Month+ Pack |
€ 73.50 EUR
NOW NAC 600mg – N-Acetyl Cysteine 100/250 Veg Capsules
From
€ 22.95 EUR
Regular price
€ 26.95 EUR
Swanson Sulforaphane from Broccoli 400 mcg – 60 Veg Capsules
€ 15.45 EUR
Regular price
€ 16.95 EUR
Swanson Full Spectrum Saw Palmetto 540 mg 100/250 Caps
From
€ 14.95 EUR
Regular price
€ 15.95 EUR
New Supplements at Probiotic.ie (Ireland)
Each new food supplement is reviewed by Probiotic.ie for ingredient quality, regulatory compliance, and fit with our evidence-led range.
Only products that meet these standards are added to this collection | Updated regularly as new, standards-compliant supplements arrive.
Reflex Nutrition Nexgen Pro Multivitamin - 90 Capsules
€ 24.95 EUR
Regular price
€ 26.95 EUR
Osavi Ashwagandha KSM-66® 200mg - 180 Vegan Capsules
€ 29.95 EUR
Regular price
€ 34.95 EUR
Healthy Origins Astaxanthin (Complex) 12mg - 60 Softgels
€ 58.50 EUR
Regular price
€ 64.50 EUR
Reflex Nutrition Creapure® Creatine Capsules - 90 Capsules
€ 14.95 EUR
Regular price
€ 17.95 EUR
KIKI Health Organic Lion's Mane Extract - 60 Vegetarian Capsules
€ 36.95 EUR
Regular price
€ 39.95 EUR
Swanson Magnesium Taurate – 100mg – 120 Vegan Tablets
€ 27.95 EUR
Regular price
€ 29.95 EUR
NOW Foods Astaxanthin 4mg – 60 Vegetarian Softgels
€ 22.95 EUR
Regular price
€ 24.95 EUR
Osavi PQQ 20mg – 60 Vegan Capsules
€ 34.50 EUR
Regular price
€ 38.95 EUR
Why Irish Customers Trust Probiotic.ie
We’re an Irish-owned specialist store focused on evidence-led probiotics and supplements, including Ireland’s exclusive access to the original De Simone formulation.
Since 2019, we’ve helped thousands of customers across Ireland choose products based on formulation quality, clinical heritage, and real-world use — not trends or marketing claims.
Our service is independently rated 4.9 out of 5 on Trustpilot, based on hundreds of verified Irish customer reviews, reflecting consistent feedback on fast delivery, product quality, and responsive support.
Every product we stock is selected by us, handled correctly, and shipped from Ireland, with local customer support if you ever need help.
You’re not buying from a faceless marketplace. You’re buying from a real Irish team that stands behind every order.
⭐ 4.9★ independent rating on Trustpilot
🇮🇪 Irish-owned and operated since 2019
🧪 Evidence-led product selection
📦 Fast delivery from Ireland
💬 Real human customer support
Start With the Right Place
Choosing supplements shouldn’t be confusing. We’ve organised our range into four clear starting points, depending on what you’re looking for.
Probiotic.ie is Ireland’s evidence-led supplements store. Start with our official De Simone CDS22-formula or explore trusted supplement paths below.
Probiotic.ie Expert Gut Health & Supplement Guides for Ireland
Cho et al. (Pusan National University, Evid Based Complement Alternat Med, 2014, PMC4017725) ran a randomised, double-blind, placebo-controlled trial in 76 men with androgenetic alopecia, reporting increased hair count after 24 weeks on a branded, manufacturer-funded 400 mg/day pumpkin seed oil capsule versus placebo, while the 5-alpha-reductase mechanism behind it has been shown only in animal models. This Ireland evidence guide covers pumpkin seed oil's fatty-acid composition, the human hair, prostate and overactive-bladder trials (Hong 2009, Nishimura 2014), the saw palmetto combination, capsules versus cold-pressed culinary oil, dosage and safety, and Swanson Pumpkin Seed Oil 1000mg (100 gelatin softgels, EUR 16.95) dispatched next-day from Dublin under FSAI food supplement rules.
Read moreA 2021 systematic review and meta-analysis by de Miranda, Weimer and Rossi (UNISINOS, Int J Dermatol 2021;60(12):1449-1461, PMID 33742704) reported gains in skin hydration and elasticity from hydrolysed collagen peptides, while a 2025 Am J Med meta-analysis by Myung and Park found the effect was smaller once industry-funded trials were separated out. This Ireland evidence guide covers whether collagen works, how types I, II and III differ by dose and mechanism, marine vs bovine sources, the EFSA claim position, dosage, safety, and the collagen range at Probiotic.ie from EUR 19.95, dispatched from Dublin.
Read moreWomen store 70–80% less creatine than men (Smith-Ryan et al., Nutrients, 2021, PMID 33800439), and the EU authorises the claim that creatine increases physical performance in successive bursts of short-term, high-intensity exercise at a 3 g/day intake (Regulation 432/2012) — a claim that applies to women and men alike. This Ireland guide covers creatine for women across strength, the menopause transition and the over-55 muscle-strength claim, dosing, the water-weight and "bloating" question, safety, and the vegan Reflex CreaPure® Creatine Powder (500g, €34.95) with next-day dispatch from Dublin under FSAI food-supplement rules.
Read moreThe International Society of Sports Nutrition (Kreider et al., J Int Soc Sports Nutr, 2017, PMID 28615996) describes creatine monohydrate as the most effective ergogenic nutritional supplement for high-intensity exercise capacity and lean mass, and the EU authorises the claim that creatine increases physical performance in successive bursts of short-term, high-intensity exercise at a 3 g/day intake (Regulation 432/2012). This Ireland guide covers creatine forms, CreaPure® purity, dosing (loading versus daily 3–5 g), the evidence for women and over-55s, cognition claims and their limits, kidney and hair-loss safety questions, and Reflex CreaPure® Creatine Powder 500g (€34.95) and Capsules (€14.95) with next-day dispatch from Dublin under FSAI food-supplement rules.
Read moreKato-Kataoka et al. (J Clin Biochem Nutr, 2010, PMID 21103034) found soy-derived phosphatidylserine improved delayed verbal recall in elderly adults over six months, while Hellhammer et al. (Lipids Health Dis, 2014, PMID 25081826) recorded significant ACTH normalisation (p=0.010) in the highest-stress subgroup of men taking 400mg/day. This Ireland guide covers phosphatidylserine's mechanism, EFSA claim status, cortisol and memory evidence, dosage and safety, and Swanson Phosphatidylserine 100mg (30 softgels, €18.90) — regulated under FSAI food supplement guidelines with nationwide Ireland delivery.
Read moreShmalberg et al. (University of Florida, Frontiers in Veterinary Science, 2019;6:163, PMID 31275948) randomised 60 dogs with acute diarrhoea and found no statistically significant difference between a probiotic, metronidazole and placebo (3.5 vs 4.6 vs 4.8 days to acceptable faecal consistency, p = 0.17), while the ACVIM-endorsed consensus statement on canine chronic inflammatory enteropathy (Heilmann, Jergens et al., J Vet Intern Med 2026;40(1):aalaf017, PMID 41742497) places dietary trials first and describes probiotics as having a limited role. This Ireland evidence guide covers what canine research shows across acute diarrhoea and chronic enteropathy, which strains have been studied including Enterococcus faecium SF68 and the eight-strain De Simone Formulation, the trials that found no benefit, safety in higher-risk dogs, and why a human food supplement is not a licensed veterinary product under HPRA rules.
Read more