Ireland’s Specialist in Probiotics & High-Strength Gut Health

Home of the Original De Simone Formulation, plus expert-selected supplements.

Shop CDS22-formula

Official De Simone Formulation Distributor – Republic of Ireland

Probiotic.ie: Sole Official De Simone Distributor – Republic of Ireland

✅ Original De Simone formulation (includes CDS22-formula)

✅ Clinically studied 8-strain probiotic formulation

✅ Sole official distributor for the Republic of Ireland

Probiotic.ie is the sole official distributor of De Simone formulation probiotic products, including CDS22-formula, in the Republic of Ireland. All retail, wholesale, and clinical supply for Ireland is fulfilled through our Irish operation, with local fulfilment, customer support, and nationwide supply.

Previously marketed under names such as Vivomixx and VSL#3, CDS22-formula continues the original De Simone formulation developed by Professor Claudio De Simone. It is supplied in Ireland exclusively through authorised distribution, preserving the documented formulation lineage.

Shop CDS22-formula About the De Simone formulation

Probiotic.ie: Sole Official Supplier of the De Simone CDS22-formula Range in Ireland

The complete CDS22-formula range, based on the original De Simone formulation developed by Professor Claudio De Simone, supplied exclusively by Probiotic.ie as the sole official distributor for the Republic of Ireland

CDS22-Formula | Original De Simone Formulation Probiotic | 450 Billion CFU | 36 Sachets | One Month+ Pack |

CDS22-Formula | Original De Simone Formulation Probiotic | 450 Billion CFU | 36 Sachets | One Month+ Pack |

€ 73.50 EUR

CDS22-formula Probiotic 450B CFU | Original De Simone Formulation | 12 Sachets

CDS22-formula Probiotic 450B CFU | Original De Simone Formulation | 12 Sachets

€ 25.95 EUR

CDS22-formula Probiotic 112B CFU | Original De Simone Formulation | 20 Capsules
Save 4%

CDS22-formula Probiotic 112B CFU | Original De Simone Formulation | 20 Capsules

€ 23.95 EUR Regular price € 24.95 EUR

CDS22-formula Infant Drops – Original De Simone Formulation (2×5 ml Bottles)

CDS22-formula Infant Drops – Original De Simone Formulation (2×5 ml Bottles)

€ 17.95 EUR

Expert Selected. Evidence Led.

Expert-Selected Supplements Trusted by Irish Customers

Beyond CDS22-formula, the same Irish team behind Ireland’s sole official De Simone distributor carefully selects a focused range of supplements for quality, formulation standards, and real-world use in Ireland. From well-researched ingredients like Berberine HCl and Lion’s Mane Mushroom to essential vitamins and minerals, every product is Probiotic.ie-curated, standards-compliant, and chosen based on evidence and Irish customer demand.

Explore All Supplements

Shop Probiotics & Evidence-Led Supplements in Ireland by Category

Browse Ireland’s most searched supplement categories, including high-strength probiotics, berberine, vitamin D3, magnesium and omega-3.

Each collection is curated using real purchase data, formulation standards and ingredient transparency.

Probiotic.ie is Ireland’s official De Simone formulation distributor and a trusted source for compliant, quality-controlled food supplements with fast nationwide delivery.

Probiotics – High-strength multi-strain formulations

Berberine – 400mg and 500mg capsules

Brain & Stress Support – Ashwagandha, Lion’s Mane, NAC

Vitamin D3 – 1000IU to 5000IU formats

Magnesium – Glycinate, citrate and powder options

Omega-3 – EPA & DHA fish oil capsules

Probiotic.ie’s Most Chosen Supplements in Ireland

Selected by Probiotic.ie based on repeat purchase, long-term use, and Irish customer demand.

Swanson Berberine HCl 400 mg – Premium Herbal Supplement - 60 Caps

Swanson Berberine HCl 400 mg – Premium Herbal Supplement - 60 Caps

€ 22.95 EUR

Swanson Lion’s Mane Mushroom 500mg – 60 Capsules

Swanson Lion’s Mane Mushroom 500mg – 60 Capsules

€ 16.95 EUR

Swanson Ashwagandha 450mg - 100 Caps
Save 11%

Swanson Ashwagandha 450mg - 100 Caps

€ 15.95 EUR Regular price € 17.95 EUR

Swanson Full Spectrum Milk Thistle 500mg – 100 Capsules
Save 8%

Swanson Full Spectrum Milk Thistle 500mg – 100 Capsules

€ 15.45 EUR Regular price € 16.95 EUR

CDS22-Formula | Original De Simone Formulation Probiotic | 450 Billion CFU | 36 Sachets | One Month+ Pack |

CDS22-Formula | Original De Simone Formulation Probiotic | 450 Billion CFU | 36 Sachets | One Month+ Pack |

€ 73.50 EUR

NOW NAC 600mg – N-Acetyl Cysteine 100 Veg Capsules
Save 8%

NOW NAC 600mg – N-Acetyl Cysteine 100 Veg Capsules

€ 22.95 EUR Regular price € 24.95 EUR

Swanson Sulforaphane from Broccoli 400 mcg – 60 Veg Capsules
Save 8%

Swanson Sulforaphane from Broccoli 400 mcg – 60 Veg Capsules

€ 15.45 EUR Regular price € 16.95 EUR

Swanson Full Spectrum Saw Palmetto 540 mg 100/250 Caps
Save 3%

Swanson Full Spectrum Saw Palmetto 540 mg 100/250 Caps

From € 15.45 EUR Regular price € 15.95 EUR

New Supplements at Probiotic.ie (Ireland)

Each new food supplement is reviewed by Probiotic.ie for ingredient quality, regulatory compliance, and fit with our evidence-led range.

Only products that meet these standards are added to this collection | Updated regularly as new, standards-compliant supplements arrive.

Wiseshrooms Lion’s Mane 3000mg 90 Capsules | Food Supplement | Fast Delivery Ireland

Wiseshrooms Lion’s Mane 3000mg 90 Capsules | Food Supplement | Fast Delivery Ireland

€ 19.95 EUR

Carlson Labs Super Omega-3 1200mg Fish Oil 100 + 30 Free Softgels | EPA & DHA | Food Supplement

Carlson Labs Super Omega-3 1200mg Fish Oil 100 + 30 Free Softgels | EPA & DHA | Food Supplement

€ 42.50 EUR

Jarrow Formulas Zinc Balance 15mg 100 Capsules | Food Supplement | Ireland

Jarrow Formulas Zinc Balance 15mg 100 Capsules | Food Supplement | Ireland

€ 17.95 EUR

Jarrow Formulas Jarro-Dophilus EPS 10 Billion CFU 120 Veg Capsules

Jarrow Formulas Jarro-Dophilus EPS 10 Billion CFU 120 Veg Capsules

€ 44.95 EUR

Doctor’s Best CoQ10 100mg 120 Softgels | Ireland

Doctor’s Best CoQ10 100mg 120 Softgels | Ireland

€ 36.95 EUR

NOW Vitamin D3 & K2 1,000 IU / 45 mcg – 120 Veg Capsules | Food Supplement | Ireland

NOW Vitamin D3 & K2 1,000 IU / 45 mcg – 120 Veg Capsules | Food Supplement | Ireland

€ 18.95 EUR

Swanson Lactobacillus Acidophilus 1 Billion CFU 100 Capsules | Probiotic Supplement Ireland

Swanson Lactobacillus Acidophilus 1 Billion CFU 100 Capsules | Probiotic Supplement Ireland

€ 11.95 EUR

Swanson Lactobacillus Rhamnosus with FOS 5 Billion CFU – 60 Veg Capsules

Swanson Lactobacillus Rhamnosus with FOS 5 Billion CFU – 60 Veg Capsules

€ 14.95 EUR

Why Irish Customers Trust Probiotic.ie

We’re an Irish-owned specialist store focused on evidence-led probiotics and supplements, including Ireland’s exclusive access to the original De Simone formulation.

Since 2019, we’ve helped thousands of customers across Ireland choose products based on formulation quality, clinical heritage, and real-world use — not trends or marketing claims.

Our service is independently rated 4.9 out of 5 on Trustpilot, based on hundreds of verified Irish customer reviews, reflecting consistent feedback on fast delivery, product quality, and responsive support.

Every product we stock is selected by us, handled correctly, and shipped from Ireland, with local customer support if you ever need help.

You’re not buying from a faceless marketplace. You’re buying from a real Irish team that stands behind every order.

⭐ 4.9★ independent rating on Trustpilot
🇮🇪 Irish-owned and operated since 2019
🧪 Evidence-led product selection
📦 Fast delivery from Ireland
💬 Real human customer support

Start With the Right Place

Choosing supplements shouldn’t be confusing. We’ve organised our range into four clear starting points, depending on what you’re looking for.

Probiotic.ie is Ireland’s evidence-led supplements store. Start with our official De Simone CDS22-formula or explore trusted supplement paths below.

Start with CDS22-formula Probiotic | The original De Simone formulation, clinically established and selected as our lead probiotic.

Gut Health Essentials | Evidence-led supplements commonly used to support digestion, balance, and everyday gut care.

Most Trusted Supplements in Ireland | Our most chosen supplements, based on verified customer use and consistent reorder demand.

Expert Guides & How to Choose | Clear, independent guides to help you choose supplements with confidence.

Probiotic.ie Expert Gut Health & Supplement Guides for Ireland

Best Probiotics in Ireland: How to Choose (2026 Guide)

By Darren Grant on Feb 11, 2026

Ireland guide: Best probiotics? No single winner—strain-specific. Checklist: strains, CFU, storage, expiry. Antibiotics: 2-hr gap, 7–14 days after. Safety + FSAI links. Not medical advice.

Read more
Probiotics With Antibiotics in Ireland: Can You Take Them Together?

By Darren Grant on Feb 11, 2026

Ireland guide: Can you take probiotics with antibiotics? Yes—2-hour gap rule. Continue 7–14 days after. AAD risk 5–30%. Safety checks, strains (LGG, S. boulardii), FSAI/HSE links. Not medical advice.

Read more
Berberine + Probiotics Ireland: Synergy for Gut, Blood Sugar and Weight

By Darren Grant on Jan 27, 2026

Berberine and probiotics are often taken together. This Ireland-first guide explains the evidence, the safety considerations, and simple timing options without hype.

Read more
Berberine Ireland: Evidence, Benefits, Side Effects & Where to Buy (2026)

By Darren Grant on Jan 24, 2026

 clear, evidence-led guide to berberine in Ireland. Learn what berberine is, what studies show, possible side effects, and how to choose a good-value supplement.

Read more
Probiotics Ireland: A Clear, Evidence-Based Guide for Irish Consumers

By Darren Grant on Dec 17, 2025

A neutral, evidence-based guide explaining probiotics in Ireland, how products differ, regulation, buying tips, and common questions for Irish consumers.

Read more
Best Probiotic for UC, IBS & Pouchitis (Ireland Evidence-Based Guide)

By Darren Grant on Dec 12, 2025

Evidence-led Ireland guide to probiotics for ulcerative colitis, pouchitis and IBS. Learn where studies are strongest, what varies by formulation, and what to ask your GP or gastro team.

Read more