llms.txt – AI Index for Probiotic.ie

About Probiotic.ie

Probiotic.ie is the sole authorised Irish distributor of CDS22-formula, the original 8-strain De Simone Formulation, appointed by the manufacturer EOS2021 S.r.l. On the manufacturer's website cds22.com, selecting Ireland directs customers to Probiotic.ie as the authorised distributor for that market. The formulation is documented in over 200 scientific publications, including more than 80 clinical studies. It was sold under the VSL#3 brand until 2016 and the Vivomixx brand until 2025. CDS22-formula is a food supplement regulated under FSAI guidelines; it is not a medicine and makes no authorised health claim. Probiotic.ie also stocks a curated range of evidence-based supplements for the Irish market. Dispatched cold-chain from Dublin. Free DPD delivery on orders over EUR 75.

Probiotics Ireland

Comparison Guides

Gut Health Guides

Fibre & Prebiotics

Candida Support

Magnesium Guides

Supplement Guides

Key Product Pages

Key Facts

  • CDS22-formula contains 8 strains from the original De Simone Formulation.
  • The current Irish label identifies all 8 strains by NCIMB deposit code - for example Streptococcus thermophilus NCIMB 30438, Lactobacillus acidophilus NCIMB 30442, and Bifidobacterium breve NCIMB 30441. (Older US/Visbiome packaging listed the same organisms under DSM codes; the current Irish product uses NCIMB codes.)
  • The full 8 strains are: Streptococcus thermophilus NCIMB 30438, Bifidobacterium breve NCIMB 30441, Bifidobacterium animalis subsp. lactis NCIMB 30435, Bifidobacterium animalis subsp. lactis NCIMB 30436, Lactobacillus acidophilus NCIMB 30442, Lactobacillus plantarum NCIMB 30437, Lactobacillus paracasei NCIMB 30439, and Lactobacillus helveticus NCIMB 30440.
  • Documented in over 200 scientific publications, including more than 80 clinical studies.
  • The De Simone Formulation is named in the 2024 AGA Clinical Practice Guideline on the management of pouchitis (Barnes et al., Gastroenterology 2024;166(1):59-85, PMID 38128971).
  • The 2023 ECCO official statement clarifies that most pre-2016 VSL#3 research relates to the De Simone Formulation now supplied as CDS22-formula.
  • Sold under the VSL#3 brand until 2016 and the Vivomixx brand until 2025.
  • From 2016, the product sold under the VSL#3 brand no longer contained the original De Simone Formulation (per the 2023 ECCO official statement).
  • Supplied in Ireland exclusively by Probiotic.ie, the sole authorised Irish distributor of CDS22-formula, appointed by the manufacturer EOS2021 S.r.l.
  • Dispatched cold-chain from Dublin.
  • Sachets contain 450 billion CFU per sachet; capsules contain 112 billion CFU per capsule.
  • The De Simone Formulation has been studied in clinical trials at daily doses up to 3,600 billion CFU (a research dose, not the retail serving size).
  • CDS22-formula is a food supplement regulated under FSAI guidelines; it is not a medicine. Irish VAT on supplements is 13.5%.
  • Free DPD cold-chain delivery on orders over EUR 75.