CDS22-Formula | Original De Simone Formulation Probiotic | 450 Billion CFU | 36 Sachets | One Month+ Pack |
CDS22-Formula | Original De Simone Formulation Probiotic | 450 Billion CFU | 36 Sachets | One Month+ Pack |
CDS22-formula 450 billion is the original 8-strain De Simone Formulation in a powder sachet, with 450 billion live bacteria (CFU) in every sachet. This is the 36-sachet pack โ a month-plus supply at one sachet a day.
It is the same formulation sold under the VSL#3 brand until 2016 and the Vivomixx brand in the EU and UK until 2025, now supplied as CDS22-formula. The identity is carried by the eight strains and their NCIMB deposit codes, not by the brand name.
A month-plus supply in one box. At one sachet a day, the 36-pack covers a full course with fewer reorders than the smaller pack. It is the size most people choose to stay consistent.
At a glance
- Format: 36 powder sachets (4.4g each) โ a month-plus supply at one a day
- Live bacteria: 450 billion CFU per sachet, across 8 strains
- Strain identity: 8 strains with NCIMB deposit codes (full list below)
- Formulation: the original De Simone Formulation (sold as VSL#3 until 2016, Vivomixx until 2025)
- Suitable for: gluten-free ยท no preservatives or synthetic sweeteners
- Storage: refrigerate +2ยฐC to +8ยฐC (stable to 25ยฐC for up to one week)
- Price & delivery: โฌ73.50 inc. Irish VAT ยท dispatched next-day from Dublin ยท free tracked Irish delivery over โฌ75
Strain composition (per sachet)
| Strain | NCIMB code | CFU per sachet |
|---|---|---|
| Streptococcus thermophilus | NCIMB 30438 | 226 billion |
| Lactobacillus acidophilus | NCIMB 30442 | 38 billion |
| Lactobacillus plantarum | NCIMB 30437 | 38 billion |
| Lactobacillus paracasei | NCIMB 30439 | 38 billion |
| Lactobacillus helveticus | NCIMB 30440 | 38 billion |
| Bifidobacterium breve | NCIMB 30441 | 24 billion |
| Bifidobacterium animalis subsp. lactis | NCIMB 30435 | 24 billion |
| Bifidobacterium animalis subsp. lactis | NCIMB 30436 | 24 billion |
| Total live bacteria per sachet | 450 billion | |
Ingredients: maltose; mixture of lactic ferments (the 8 strains above). Gluten-free. No preservatives or synthetic sweeteners. The live cell count refers to the product correctly stored in intact packaging at refrigerated temperature (+2ยฐC to +8ยฐC) until the best-before date.
Key features
- 450 billion CFU per sachet โ 8 strains, each identified by its NCIMB deposit code
- 36-sachet box โ a month-plus supply at one sachet a day
- The original De Simone Formulation (sold as VSL#3 until 2016, Vivomixx until 2025)
- Powder format โ mixes into a cool drink or yoghurt; gluten-free, no preservatives or synthetic sweeteners
- Stored refrigerated in Dublin and dispatched next-day (no Friday dispatch)
- Sole authorised Irish distributor of CDS22-formula (appointed by the manufacturer, EOS2021 S.r.l.)
How to take
Mix one sachet into a cool, non-fizzy drink or yoghurt and take it straight away. Do not use hot liquids, as heat affects live bacteria. The pack directions are 1 to 2 sachets daily for adults and children aged 7 and over, and up to half a sachet daily for children aged 3 to 6. Do not exceed the recommended daily dose. Keep refrigerated. For a young child, check with your GP or public health nurse first.
Storage and delivery in Ireland
This is a live-culture product, so both correct storage and fast delivery matter. We keep it refrigerated at our temperature-controlled facility in Dublin and dispatch orders the evening before on a tracked next-day service, so most orders arrive within about 24 hours. The sachets stay stable at room temperature (up to 25ยฐC) for up to a week, so fast tracked transit keeps them well within their safe window; refrigerate on arrival. We do not dispatch on Fridays, so your order never sits in a depot over the weekend. See our delivery information.
Other formats and the full range
- CDS22-formula 450 billion, 12-sachet pack โ the smaller box, same formulation
- CDS22-formula 112 billion capsules โ capsule format for a simple daily routine
- CDS22-formula Infant Drops โ for babies and young children
- All CDS22-formula products
Background and evidence: VSL#3 alternative Ireland ยท scientific publications ยท clinical studies bibliography ยท all guides
Frequently asked questions
What is the CDS22-formula 36-sachet pack?
It is the original 8-strain De Simone Formulation in a powder sachet, with 450 billion CFU per sachet. This is the 36-sachet box, a month-plus supply at one sachet a day. It is the same formulation sold as VSL#3 until 2016 and as Vivomixx in the EU and UK until 2025, identified by its NCIMB strain codes.
How long does a 36-sachet pack last?
At one sachet a day, a 36-sachet box is a month-plus supply, which is why many people choose this size for a full course with fewer reorders. The pack directions allow 1 to 2 sachets daily for adults and children aged 7 and over; at two a day a box lasts around 18 days. Follow the directions on the pack.
Is it the same formulation as Vivomixx and VSL#3?
Yes. It carries the De Simone Formulation, the 8-strain mixture sold as VSL#3 until 2016 and as Vivomixx in the EU and UK until 2025, now supplied as CDS22-formula. Identity is confirmed by the NCIMB strain codes rather than the brand name. VSL#3 is a trademark of VSL Pharmaceuticals Inc. and Actial S.r.l.; Vivomixx is a trademark of Mendes SA; CDS22-formula is not affiliated with them.
Which strains and how much CFU are in each sachet?
Each sachet provides 450 billion CFU across 8 strains: Streptococcus thermophilus NCIMB 30438 (226 billion), Lactobacillus acidophilus NCIMB 30442, Lactobacillus plantarum NCIMB 30437, Lactobacillus paracasei NCIMB 30439 and Lactobacillus helveticus NCIMB 30440 (38 billion each), and Bifidobacterium breve NCIMB 30441 and Bifidobacterium animalis subsp. lactis NCIMB 30435 and NCIMB 30436 (24 billion each).
How do I take the sachets?
Mix one sachet into a cool, non-fizzy drink or yoghurt and consume it straight away. Do not use hot liquids, as heat affects live bacteria. The pack directions are 1 to 2 sachets daily for adults and children aged 7 and over, and up to half a sachet daily for children aged 3 to 6. Do not exceed the recommended daily dose.
Is it gluten-free, and what are the ingredients?
The ingredients are maltose and a mixture of lactic ferments (the eight strains). It is gluten-free and contains no preservatives or synthetic sweeteners. If your household avoids specific allergens, check the current box before use.
How should it be stored, and how is it delivered in Ireland?
Store the sachets in the refrigerator at +2ยฐC to +8ยฐC. They stay stable at room temperature up to 25ยฐC for up to a week, which covers transit. We keep the product refrigerated at our temperature-controlled Dublin facility and dispatch the evening before on a tracked next-day service, so most orders arrive within about 24 hours. We do not dispatch on Fridays, so nothing sits in a depot over the weekend. Delivery is tracked across Ireland and free over โฌ75.
Who is the official Irish distributor of CDS22-formula?
Probiotic.ie is the sole authorised Irish distributor of CDS22-formula, appointed by the manufacturer EOS2021 S.r.l. On the manufacturer's website, cds22.com, selecting Ireland directs customers to Probiotic.ie. Buying from the authorised distributor is how you confirm you are receiving the genuine De Simone Formulation, stored refrigerated and shipped from Dublin.
Is CDS22-formula a medicine?
No. CDS22-formula is sold legally in Ireland as a food supplement. It is not a medicine and is not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, breastfeeding, taking medication or under medical supervision, consult a doctor or pharmacist before use.
Product details: CDS22-formula 450 billion ยท 36 powder sachets (4.4g each) ยท 450 billion CFU per sachet ยท 8 strains with NCIMB codes ยท the original De Simone Formulation ยท sole authorised Irish distributor ยท โฌ73.50 inc. Irish VAT.
VSL#3ยฎ is a registered trademark of VSL Pharmaceuticals Inc. and Actial S.r.l. Vivomixxยฎ is a registered trademark of Mendes SA. Visbiomeยฎ is a registered trademark of ExeGi Pharma. CDS22-formula is manufactured by EOS2021 S.r.l. and is not affiliated with, endorsed by, or distributed by the VSL#3, Vivomixx or Visbiome trademark holders. Historical brand names are used for identification and factual continuity only.